From in silico Protein Epitope Density Prediction to Testing Escherichia coli O157:H7 Vaccine Candidates in a Murine Model of Colonization

From in silico Protein Epitope Density Prediction to Testing Escherichia coli O157:H7 Vaccine Candidates in a Murine Model of Colonization

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a leading cause of foodborne illnesses worldwide and is a common serotype linked to hemorrhagic colitis and an important cause of hemolytic uremic syndrome (HUS). Treatment of EHEC O157:H7 infections is complicated, as antibiotics can exacerbate S...

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Bibliographic Details
Main Authors: Daniel Tapia, Brittany N Ross, Anjana Kalita, Mridul Kalita, Christopher L Hatcher, Laura A Muruato, Alfredo G Torres
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
bioinformatics
Vaccine
immunoinformatics
type III secretion system
Escherichia coli O157:H7
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00094/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00094/full

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