Identification of Tumor Microenvironment-Related Prognostic Biomarkers for Ovarian Serous Cancer 3-Year Mortality Using Targeted Maximum Likelihood Estimation: A TCGA Data Mining Study

Identification of Tumor Microenvironment-Related Prognostic Biomarkers for Ovarian Serous Cancer 3-Year Mortality Using Targeted Maximum Likelihood Estimation: A TCGA Data Mining Study

Ovarian serous cancer (OSC) is one of the leading causes of death across the world. The role of the tumor microenvironment (TME) in OSC has received increasing attention. Targeted maximum likelihood estimation (TMLE) is developed under a counterfactual framework to produce effect estimation for both...

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Bibliographic Details
Main Authors: Lu Wang, Xiaoru Sun, Chuandi Jin, Yue Fan, Fuzhong Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
targeted maximum likelihood estimation
ovarian cancer
tumor microenvironment
gene expression
prognostic biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.625145/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.625145/full

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