Methods and approaches in the topology-based analysis of biological pathways
The goal of pathway analysis is to identify the pathways significantly impacted in a given phenotype. Many current methods are based on algorithms which consider pathways as simple gene lists, dramatically under-utilizing the knowledge that such pathways are meant to capture. During the past few y...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-10-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00278/full |