4'-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice.

4'-Hydroxywogonin (4'-HW), a flavonoid, has been isolated from various plants and shown to inhibit NO production in macrophages. However, the molecular mechanisms and its in vivo activity have not been determined. Our study aimed to investigate the mechanisms underlying the anti-inflammato...

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Bibliographic Details
Main Authors: Chao Fan, Le-Hao Wu, Gu-Fang Zhang, Fangfang Xu, Shuo Zhang, Xiuli Zhang, Lei Sun, Yang Yu, Yan Zhang, Richard D Ye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5549707?pdf=render