Glutamine synthetase, Glypican-3 and Arginase-1 expression in the differential diagnosis of hepatocellular carcinoma vs. metastatic carcinomas of the liver

OBJECTIVE: Diagnosis of metastatic liver carcinomas (MLCs) vs. hepatocellular carcinomas (HCCs) may be problematic especially in the non-cirrhotic liver. Glutamine Synthetase (GS), Glypican3 (GPC3, and Arginase-1 (Arg-1) immunohistochemistry can demonstrate the hepatocellular origin of a given tumor...

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Bibliographic Details
Main Authors: A. Argon, D. Nart, S. Erbil, F. Yilmaz Barbet
Format: Article
Language:English
Published: Verduci Editore 2019-05-01
Series:World Cancer Research Journal
Subjects:
hcc
Online Access:https://www.wcrj.net/wp-content/uploads/sites/5/2019/07/e1297-Glutamine-synthetase-Glypican-3-and-Arginase-1-expression-in-the-differential-diagnosis-of-hepatocellular-carcinoma-vs.-metastatic-carcinomas-of-the-liver.pdf