Establishment of a Recombinant AAV2/HBoV1 Vector Production System in Insect Cells

We have previously developed an rAAV2/HBoV1 vector in which a recombinant adeno-associated virus 2 (rAAV2) genome is pseudopackaged into a human bocavirus 1 (HBoV1) capsid. Recently, the production of rAAV2/HBoV1 in human embryonic kidney (HEK) 293 cells has been greatly improved in the absence of a...

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Bibliographic Details
Main Authors: Xuefeng Deng, Wei Zou, Ziying Yan, Jianming Qiu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/4/439