Inhibitors of Testosterone Biosynthetic and Metabolic Activation Enzymes

The Leydig cells of the testis have the capacity to biosynthesize testosterone from cholesterol. Testosterone and its metabolically activated product dihydrotestosterone are critical for the development of male reproductive system and spermatogenesis. At least four steroidogenic enzymes are involved...

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Bibliographic Details
Main Authors: Leping Ye, Ren-Shan Ge, Zhi-Jian Su
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/12/9983/