Molecular scanning of the human PPARα gene: association of the L162V mutation with hyperapobetalipoproteinemia

Molecular scanning of the human PPARα gene: association of the L162V mutation with hyperapobetalipoproteinemia

Peroxisome proliferator-activated receptor alpha (PPARα) is a member of the steroid hormone receptor super family involved in the control of cellular lipid utilization. This makes PPARα a candidate gene for type 2 diabetes and dyslipidemia. The aim of this study was to investigate whether genetic va...

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Bibliographic Details
Main Authors: Marie-Claude Vohl, Pierre Lepage, Daniel Gaudet, Carl G. Brewer, Christine Bétard, Patrice Perron, Ghislaine Houde, Christine Cellier, Janet M. Faith, Jean-Pierre Després, Kenneth Morgan, Thomas J. Hudson
Format: Article
Language:English
Published: Elsevier 2000-06-01
Series:Journal of Lipid Research
Subjects:
PPARα
L162V mutation
type 2 diabetes
apolipoprotein B
hyperapobetalipoproteinemia
genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032037X

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http://www.sciencedirect.com/science/article/pii/S002222752032037X

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