Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design

Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design

Abstract Background Osteoarthritis (OA) leads to joint failure and total joint replacement (TJR, either hip (H) or knee (K)). Worsening of pain and joint space narrowing are believed to be surrogates for joint failure; however, we hypothesize that TJR, as a reflection of joint failure, can be used a...

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Bibliographic Details
Main Authors: Cecilie L. Bager, Morten Karsdal, Asger Bihlet, Christian Thudium, Inger Byrjalsen, Anne C. Bay-Jensen
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Musculoskeletal Disorders
Subjects:
Total joint replacements
Osteoarthritis
Clinical trial design
Postmenopausal women
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Online Access:http://link.springer.com/article/10.1186/s12891-019-2680-3

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http://link.springer.com/article/10.1186/s12891-019-2680-3

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