Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate

Abstract Dengue virus (DENV) infection is the most common mosquito-transmitted viral infection. DENV infection can cause mild dengue fever or severe dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). Hemorrhage and vascular leakage are two characteristic symptoms of DHF/DSS. However, due to...

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Bibliographic Details
Main Authors: Hong-Ru Chen, Yen-Chung Lai, Trai-Ming Yeh
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-018-0462-0