Scientific Evidence and Rationale for the Development of Curcumin and Resveratrol as Nutraceutricals for Joint Health

Interleukin 1β (IL-1β) and tumor necrosis factor α (TNF-α) are key cytokines that drive the production of inflammatory mediators and matrix-degrading enzymes in osteoarthritis (OA). These proinflammatory cytokines bind to their respective cell surface receptors and activate inflammatory signaling pa...

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Bibliographic Details
Main Authors: Yves Henrotin, Mehdi Shakibaei, Hans-Konrad Biesalski, Ali Mobasheri
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:International Journal of Molecular Sciences
Subjects:
OA
RA
Online Access:http://www.mdpi.com/1422-0067/13/4/4202/