NAIP–NLRC4-deficient mice are susceptible to shigellosis

Bacteria of the genus Shigella cause shigellosis, a severe gastrointestinal disease that is a major cause of diarrhea-associated mortality in humans. Mice are highly resistant to Shigella and the lack of a tractable physiological model of shigellosis has impeded our understanding of this important h...

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Bibliographic Details
Main Authors: Patrick S Mitchell, Justin L Roncaioli, Elizabeth A Turcotte, Lisa Goers, Roberto A Chavez, Angus Y Lee, Cammie F Lesser, Isabella Rauch, Russell E Vance
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/59022