Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary study.

Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary study.

<h4>Background</h4>Identifying predictive biomarkers of drug response is of key importance to improve therapy management and drug selection in cancer therapy. To date, the influence of drug exposure and pharmacogenetic variants on sorafenib-induced toxicity remains poorly documented. The...

Full description

Bibliographic Details
Main Authors: Pascaline Boudou-Rouquette, Céline Narjoz, Jean Louis Golmard, Audrey Thomas-Schoemann, Olivier Mir, Fabrice Taieb, Jean-Philippe Durand, Romain Coriat, Alain Dauphin, Michel Vidal, Michel Tod, Marie-Anne Loriot, François Goldwasser, Benoit Blanchet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912756/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912756/pdf/?tool=EBI

Similar Items