The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in MiceSummary

The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in MiceSummary

Background & Aims: Liver fibrosis is a multifactorial trait that develops in response to chronic liver injury. Our aim was to characterize the genetic architecture of carbon tetrachloride (CCl4)-induced liver fibrosis using the Hybrid Mouse Diversity Panel, a panel of more than 100 genetical...

Full description

Bibliographic Details
Main Authors: Iina Tuominen, Brie K. Fuqua, Calvin Pan, Nicole Renaud, Kevin Wroblewski, Mete Civelek, Kara Clerkin, Ashot Asaryan, Sara G. Haroutunian, Joseph Loureiro, Jason Borawski, Guglielmo Roma, Judith Knehr, Walter Carbone, Samuel French, Brian W. Parks, Simon T. Hui, Margarete Mehrabian, Clara Magyar, Rita M. Cantor, Chinweike Ukomadu, Aldons J. Lusis, Simon W. Beaven
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
CCl4
Systems Genetics
Liver Toxicity and Injury
Genome-Wide Association Study
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X2030134X

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X2030134X

Similar Items