Acute dapagliflozin administration exerts cardioprotective effects in rats with cardiac ischemia/reperfusion injury

Acute dapagliflozin administration exerts cardioprotective effects in rats with cardiac ischemia/reperfusion injury

Abstract Background A sodium-glucose co-transporter 2 (SGLT-2) inhibitor had favorable impact on the attenuation of hyperglycemia together with the severity of heart failure. However, the effects of acute dapagliflozin administration at the time of cardiac ischemia/reperfusion (I/R) injury are not e...

Full description

Bibliographic Details
Main Authors: Sarayut Lahnwong, Siripong Palee, Nattayaporn Apaijai, Sirawit Sriwichaiin, Sasiwan Kerdphoo, Thidarat Jaiwongkam, Siriporn C. Chattipakorn, Nipon Chattipakorn
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cardiovascular Diabetology
Subjects:
Heart
Ischemia–reperfusion injury
Sodium-glucose co-transporter 2 (SGLT-2) inhibitors
Dapagliflozin
Mitochondria
Online Access:http://link.springer.com/article/10.1186/s12933-020-01066-9

Internet

http://link.springer.com/article/10.1186/s12933-020-01066-9

Similar Items