Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease[S]

Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease[S]

Promoter polymorphisms in microsomal triglyceride transfer protein (MTTP) have been associated with decreased plasma lipids but an increased risk for ischemic heart disease (IHD), indicating that MTTP influences the susceptibility for IHD independent of plasma lipids. The objective of this study was...

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Bibliographic Details
Main Authors: Anna Aminoff, Helena Ledmyr, Petra Thulin, Kerstin Lundell, Leyla Nunez, Elisabeth Strandhagen, Charlotte Murphy, Ulf Lidberg, Jukka Westerbacka, Anders Franco-Cereceda, Jan Liska, Lars Bo Nielsen, Mats Gåfvels, Maria Nastase Mannila, Anders Hamsten, Hannele Yki-Järvinen, Dag Thelle, Per Eriksson, Jan Borén, Ewa Ehrenborg
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Lipid Research
Subjects:
promoter activity
lipotoxicity
lipid accumulation
myocardium
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313808

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http://www.sciencedirect.com/science/article/pii/S0022227520313808

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