DISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disorders

DISC1 was discovered in a Scottish pedigree in which a chromosomal translocation that breaks this gene segregates with psychiatric disorders, mainly depression and schizophrenia. Linkage and association studies in diverse populations support DISC1 as a susceptibility gene to a variety of neuropsychi...

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Bibliographic Details
Main Authors: Tyler eCash-Padgett, Hanna eJaaro-Peled
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00113/full