Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPBy/y mice model

Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPBy/y mice model

Abstract Background The basal transcription/repair factor TFIIH is a ten sub-unit complex essential for RNA polymerase II (RNAP2) transcription initiation and DNA repair. In both these processes TFIIH acts as a DNA helix opener, required for promoter escape of RNAP2 in transcription initiation, and...

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Bibliographic Details
Main Authors: Lise-Marie Donnio, Catherine Miquel, Wim Vermeulen, Giuseppina Giglia-Mari, Pierre-Olivier Mari
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Cancer Cell International
Subjects:
TFIIH
Transcription
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12935-019-0945-4

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http://link.springer.com/article/10.1186/s12935-019-0945-4

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