Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPBy/y mice model
Abstract Background The basal transcription/repair factor TFIIH is a ten sub-unit complex essential for RNA polymerase II (RNAP2) transcription initiation and DNA repair. In both these processes TFIIH acts as a DNA helix opener, required for promoter escape of RNAP2 in transcription initiation, and...
Main Authors: | Lise-Marie Donnio, Catherine Miquel, Wim Vermeulen, Giuseppina Giglia-Mari, Pierre-Olivier Mari |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-09-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-019-0945-4 |
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