Cardiac Toxicity of Chloroquine or Hydroxychloroquine in Patients With COVID-19: A Systematic Review and Meta-regression Analysis

Objective: To systematically review the literature and to estimate the risk of chloroquine (CQ) and hydroxychloroquine (HCQ) cardiac toxicity in patients with coronavirus disease 2019 (COVID-19). Methods: We searched multiple data sources including PubMed/MEDLINE, Ovid Embase, Ovid EBM Reviews, Scop...

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Main Authors: Imad M. Tleyjeh, MD, MSc, Zakariya Kashour, MD, MSc, Oweida AlDosary, MD, Muhammad Riaz, PhD, Haytham Tlayjeh, MD, Musa A. Garbati, MD, Rana Tleyjeh, Mouaz H. Al-Mallah, MD, MSc, M. Rizwan Sohail, MD, Dana Gerberi, MLIS, Aref A. Bin Abdulhak, MD, MSc, John R. Giudicessi, MD, PhD, Michael J. Ackerman, MD, PhD, Tarek Kashour, MBChB
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2542454820302058