Impact of Methods on the Measurement of mRNA Turnover

The turnover of the RNA molecules is determined by the rates of transcription and RNA degradation. Several methods have been developed to study RNA turnover since the beginnings of molecular biology. Here we summarize the main methods to measure RNA half-life: transcription inhibition, gene control,...

Full description

Bibliographic Details
Main Authors: Takeo Wada, Attila Becskei
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
NMD
4sU
Online Access:https://www.mdpi.com/1422-0067/18/12/2723