Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus

Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus

Leishmania is a parasitic protozoon responsible for the neglected tropical disease Leishmaniasis. Approximately, 350 million people are susceptible and close to 70,000 death cases globally are reported annually. The lack of effective leishmanicides, the emergence of drug resistance and toxicity conc...

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Bibliographic Details
Main Authors: Justice Afrifa Crentsil, Lauve Rachel Tchokouaha Yamthe, Barbara Zenabu Anibea, Emmanuel Broni, Samuel Kojo Kwofie, John Kweku Amissah Tetteh, Dorcas Osei-Safo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Croton sylvaticus
hardwickiic acid
leishmaniasis
structural modeling
molecular docking
trypanothione reductase
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00753/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00753/full

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