Mahanine exerts in vitro and in vivo antileishmanial activity by modulation of redox homeostasis

Abstract Earlier we have established a carbazole alkaloid (mahanine) isolated from an Indian edible medicinal plant as an anticancer agent with minimal effect on normal cells. Here we report for the first time that mahanine-treated drug resistant and sensitive virulent Leishmania donovani promastigo...

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Bibliographic Details
Main Authors: Saptarshi Roy, Devawati Dutta, Eswara M. Satyavarapu, Pawan K. Yadav, Chhabinath Mandal, Susanta Kar, Chitra Mandal
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03943-y