Imputing single-cell RNA-seq data by combining graph convolution and autoencoder neural networks
Summary: Single-cell RNA sequencing technology promotes the profiling of single-cell transcriptomes at an unprecedented throughput and resolution. However, in scRNA-seq studies, only a low amount of sequenced mRNA in each cell leads to missing detection for a portion of mRNA molecules, i.e. the drop...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221003618 |