GLP-2 Suppresses LPS-Induced Inflammation in Macrophages by Inhibiting ERK Phosphorylation and NF-κB Activation

GLP-2 Suppresses LPS-Induced Inflammation in Macrophages by Inhibiting ERK Phosphorylation and NF-κB Activation

Background/Aims: GLP-2 has been shown to exert anti-inflammatory effects, but the underlying molecular mechanisms remained undefined. As macrophages are important in the development and maintenance of inflammation, we investigated whether exogenous GLP-2 modulates the expression of pro-inflammatory...

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Bibliographic Details
Main Authors: Shanshan Xie, Bingrun Liu, Shoupeng Fu, Wei Wang, Yunhou Yin, Nan Li, Wei Chen, Juxiong Liu, Dianfeng Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
GLP-2
Pro-inflammatory cytokines
ERK
NF-κB
Online Access:http://www.karger.com/Article/FullText/363025

Internet

http://www.karger.com/Article/FullText/363025

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