Role of GSTM1 and GSTT1 genotypes in differentiated thyroid cancer and interaction with lifestyle factors: Results from case-control studies in France and New Caledonia.

BACKGROUND:GSTM1 and GSTT1 are involved in detoxification of xenobiotics, products of oxidative stress and in steroid hormones metabolism. We investigated whether GSTM1 and GSTT1 gene deletion was associated with DTC risk and explored interaction with non-genetic risk factors of DTC. METHODS:The stu...

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Main Authors: Catherine Tcheandjieu, Emilie Cordina-Duverger, Claire Mulot, Dominique Baron-Dubourdieu, Anne-Valérie Guizard, Claire Schvartz, Pierre Laurent-Puig, Pascal Guénel, Thérèse Truong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228187