Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication
<p>Abstract</p> <p>A series of amino acid substitutions (M239F, M239G, P240F, V241G) were placed in the p10-CA protease cleavage site (VVAM*PVVI) to change the rate of cleavage of the junction. The effects of these substitutions on p10-CA cleavage by RSV PR were confirmed by measur...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-09-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/2/1/58 |