Activation of host translational control pathways by a viral developmental switch.

In response to numerous signals, latent herpesvirus genomes abruptly switch their developmental program, aborting stable host-cell colonization in favor of productive viral replication that ultimately destroys the cell. To achieve a rapid gene expression transition, newly minted capped, polyadenylat...

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Bibliographic Details
Main Authors: Carolina Arias, Derek Walsh, Jack Harbell, Angus C Wilson, Ian Mohr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19300492/?tool=EBI