Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjögren’s syndrome differ in molecular signatures and treatment perspectives

Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjögren’s syndrome differ in molecular signatures and treatment perspectives

Abstract Background Previous studies and own clinical observations of patients with systemic lupus erythematosus (SLE) suggest that SLE harbors distinct immunophenotypes. This heterogeneity might result in differences in response to treatment in different subgroups and obstruct clinical trials. Our...

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Bibliographic Details
Main Authors: Helena Idborg, Arash Zandian, Ann-Sofi Sandberg, Bo Nilsson, Kerstin Elvin, Lennart Truedsson, Azita Sohrabian, Johan Rönnelid, John Mo, Giorgia Grosso, Marika Kvarnström, Iva Gunnarsson, Janne Lehtiö, Peter Nilsson, Elisabet Svenungsson, Per-Johan Jakobsson
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Arthritis Research & Therapy
Subjects:
Systemic lupus erythematosus
Antiphospholipid syndrome
Sjögren’s syndrome
Personalized medicine
Affinity-based proteomics
Subgroups
Online Access:http://link.springer.com/article/10.1186/s13075-019-1836-8

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http://link.springer.com/article/10.1186/s13075-019-1836-8

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