Vertically transferred maternal immune cells promote neonatal immunity against early life infections

Vertically transferred maternal immune cells promote neonatal immunity against early life infections

Maternal immune cells seed into the foetus during mammalian pregnancy, yet the functional role of these cells is unclear. Here the authors show that maternal immune cells in foetal bone marrow stimulate immune development, subsequently reducing the risk or severity of infections in newborns.

Bibliographic Details
Main Authors: Ina Annelies Stelzer, Christopher Urbschat, Steven Schepanski, Kristin Thiele, Ioanna Triviai, Agnes Wieczorek, Malik Alawi, Denise Ohnezeit, Julian Kottlau, Jiabin Huang, Nicole Fischer, Hans-Willi Mittrücker, Maria Emilia Solano, Boris Fehse, Anke Diemert, Felix R. Stahl, Petra Clara Arck
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24719-z

Internet

https://doi.org/10.1038/s41467-021-24719-z

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