Insulin-Like Growth Factor Binding Protein 6 in Rheumatoid Arthritis: A Possible Novel Chemotactic Factor?

Insulin-Like Growth Factor Binding Protein 6 in Rheumatoid Arthritis: A Possible Novel Chemotactic Factor?

ObjectivesImmune cell migration from the bloodstream to target tissues is a hallmark of rheumatoid arthritis (RA) pathogenesis. The role of chemoattractants, mainly chemokines, and their possible targeting for therapeutic purposes have been under intense investigation over the last few years but the...

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Bibliographic Details
Main Authors: Alessia Alunno, Onelia Bistoni, Mirko Manetti, Giacomo Cafaro, Valentina Valentini, Elena Bartoloni, Roberto Gerli, Arcangelo Liso
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
IGFBP6
cell migration
synovial membrane
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00554/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00554/full

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