High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes.

High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes.

Despite the widespread use of kinase-targeted agents in clear cell renal cell carcinoma (CC-RCC), comprehensive kinase activity evaluation (kinomic profiling) of these tumors is lacking. Thus, kinomic profiling of CC-RCC may assist in devising a classification system associated with clinical outcome...

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Bibliographic Details
Main Authors: Joshua C Anderson, Christopher D Willey, Amitkumar Mehta, Karim Welaya, Dongquan Chen, Christine W Duarte, Pooja Ghatalia, Waleed Arafat, Ankit Madan, Sunil Sudarshan, Gurudatta Naik, William E Grizzle, Toni K Choueiri, Guru Sonpavde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4583516?pdf=render

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http://europepmc.org/articles/PMC4583516?pdf=render

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