High-dose pharmaceutical grade biotin (MD1003) in amyotrophic lateral sclerosis: A pilot study

High-dose pharmaceutical grade biotin (MD1003) in amyotrophic lateral sclerosis: A pilot study

Background: Oligodendrocytes (OGs) provide metabolic support to motor neurons (MNs) and are implicated in the pathophysiology of amyotrophic lateral sclerosis (ALS). MD1003, or high-dose Pharmaceutical grade Biotin (hdPB), may improve disability in progressive multiple sclerosis patients via augment...

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Bibliographic Details
Main Authors: Raul Juntas-Morales, Nicolas Pageot, Abdelkarim Bendarraz, Sébastien Alphandéry, Frédéric Sedel, Stéphanie Seigle, William Camu
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537019302639

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http://www.sciencedirect.com/science/article/pii/S2589537019302639

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