Differential Activation of ERK Signaling in HPV-Related Oropharyngeal Squamous Cell Carcinoma

Differential Activation of ERK Signaling in HPV-Related Oropharyngeal Squamous Cell Carcinoma

Human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) forms a distinct tumor entity with better survival clinical outcome. Numerous underlying molecular mechanisms have been postulated for differences in treatment response, but the impact of MEK/ERK signaling, a main drive...

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Bibliographic Details
Main Authors: Chao Rong, Marie Muller, Christa Flechtenmacher, Dana Holzinger, Gerhard Dyckhoff, Olcay Cem Bulut, Dominik Horn, Peter Plinkert, Jochen Hess, Annette Affolter
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
oropharyngeal squamous cell carcinoma
MAPK/ERK
AKT
prognostic biomarker
human papillomavirus
tissue microarray
Online Access:https://www.mdpi.com/2072-6694/11/4/584

Internet

https://www.mdpi.com/2072-6694/11/4/584

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