Whole genome sequencing to investigate the emergence of clonal complex 23 Neisseria meningitidis serogroup Y disease in the United States.

Whole genome sequencing to investigate the emergence of clonal complex 23 Neisseria meningitidis serogroup Y disease in the United States.

In the United States, serogroup Y, ST-23 clonal complex Neisseria meningitidis was responsible for an increase in meningococcal disease incidence during the 1990s. This increase was accompanied by antigenic shift of three outer membrane proteins, with a decrease in the population that predominated i...

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Bibliographic Details
Main Authors: Mary G Krauland, Julie C Dunning Hotopp, David R Riley, Sean C Daugherty, Jane W Marsh, Nancy E Messonnier, Leonard W Mayer, Hervé Tettelin, Lee H Harrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338715?pdf=render

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http://europepmc.org/articles/PMC3338715?pdf=render

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