Cypin: A novel target for traumatic brain injury

Cypin: A novel target for traumatic brain injury

Cytosolic PSD-95 interactor (cypin), the primary guanine deaminase in the brain, plays key roles in shaping neuronal circuits and regulating neuronal survival. Despite this pervasive role in neuronal function, the ability for cypin activity to affect recovery from acute brain injury is unknown. A ke...

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Bibliographic Details
Main Authors: Przemyslaw Swiatkowski, Emily Sewell, Eric S. Sweet, Samantha Dickson, Rachel A. Swanson, Sara A. McEwan, Nicholas Cuccolo, Mark E. McDonnell, Mihir V. Patel, Nevin Varghese, Barclay Morrison, Allen B. Reitz, David F. Meaney, Bonnie L. Firestein
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Neurobiology of Disease
Subjects:
Cypin
Traumatic brain injury
Glutamate-induced toxicity
Guanine deaminase activity
Electrophysiology
Controlled cortical impact
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118302882

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http://www.sciencedirect.com/science/article/pii/S0969996118302882

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