The central role of RNA in the genetic programming of complex organisms

The central role of RNA in the genetic programming of complex organisms

Notwithstanding lineage-specific variations, the number and type of protein-coding genes remain relatively static across the animal kingdom. By contrast there has been a massive expansion in the extent of genomic non-proteincoding sequences with increasing developmental complexity. These non-coding...

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Bibliographic Details
Main Author: John S. Mattick
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2010-12-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
desenvolvimento
RNA não-codificador
epi-genoma
regulação gênica
edição de RNA
cérebro
development
noncoding RNA
epigenome
gene regulation
RNA editing
brain
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000400016

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000400016

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