Insights into Cardiac IKs (KCNQ1/KCNE1) Channels Regulation

The delayed rectifier potassium IKs channel is an important regulator of the duration of the ventricular action potential. Hundreds of mutations in the genes (<i>KCNQ1</i> and <i>KCNE1</i>) encoding the IKs channel cause long QT syndrome (LQTS). LQTS is a heart disorder that...

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Bibliographic Details
Main Authors: Xiaoan Wu, H. Peter Larsson
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
IKs
Online Access:https://www.mdpi.com/1422-0067/21/24/9440