MMP-13, p53 in the Progression of Malignant Peripheral Nerve Sheath Tumors

MMP-13, p53 in the Progression of Malignant Peripheral Nerve Sheath Tumors

Malignant peripheral nerve sheath tumors (MPNST) are sarcomas with poor prognosis, limited treatment options. Factors contributing to tumor progression are largely unknown. We therefore examined MPNST from 22 neurofibromatosis type 1 (NF1) patients, 14 nonNF1 patients, 14 neurofibroma patients for...

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Bibliographic Details
Main Authors: Nikola Holtkamp, Isis Atallah, Ali-Fuat Okuducu, Jana Mucha, Christian Hartmann, Victor-F Mautner, Reinhard E. Friedrich, Christian Mawrin, Andreas von Deimling
Format: Article
Language:English
Published: Elsevier 2007-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Malignant peripheral nerve sheath tumor
matrix metalloproteinase 13
neurofibromatosis type 1
TP53
malignant progression
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800741

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http://www.sciencedirect.com/science/article/pii/S1476558607800741

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