B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments
Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto-myosin cytoskeleton. While cytoskeleton organizati...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/48093 |