B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments

Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto-myosin cytoskeleton. While cytoskeleton organizati...

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Bibliographic Details
Main Authors: Sophie I Roper, Laabiah Wasim, Dessislava Malinova, Michael Way, Susan Cox, Pavel Tolar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/48093