Age does not influence the disease course in a mouse model of Streptococcus pneumoniae serotype 3 meningitis

Age does not influence the disease course in a mouse model of Streptococcus pneumoniae serotype 3 meningitis

Abstract In order to elucidate the causes for the increased mortality of aged patients with bacterial central nervous system (CNS) infections, we compared the course of Streptococcus pneumoniae (S. pneumoniae) meningitis in aged and young mice. Aged (21.2 ± 3.1 months, n = 40) and young (3.2 ± 0.9 m...

Full description

Bibliographic Details
Main Authors: Anja Manig, Sandra Ribes, Catharina Diesselberg, Stephanie Bunkowski, Roland Nau, Sandra Schütze
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Immunity & Ageing
Subjects:
Immunosenescence
Age
Mouse model
Streptococcus pneumoniae
Bacterial meningitis
Survival
Online Access:http://link.springer.com/article/10.1186/s12979-018-0129-4

Internet

http://link.springer.com/article/10.1186/s12979-018-0129-4

Similar Items