Acute Neurofilament Light Chain Plasma Levels Correlate With Stroke Severity and Clinical Outcome in Ischemic Stroke Patients

Acute Neurofilament Light Chain Plasma Levels Correlate With Stroke Severity and Clinical Outcome in Ischemic Stroke Patients

Background: Ischemic stroke causes increased blood–brain barrier permeability and release of markers of axonal damage and inflammation. To investigate diagnostic and prognostic roles of neurofilament light chain (NF-L), we assessed levels of NF-L, S100B, interleukin-6 (IL-6), E-selectin, vascular en...

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Bibliographic Details
Main Authors: Helle H. Nielsen, Catarina B. Soares, Sofie S. Høgedal, Jonna S. Madsen, Rikke B. Hansen, Alex A. Christensen, Charlotte Madsen, Bettina H. Clausen, Lars Henrik Frich, Matilda Degn, Christian Sibbersen, Kate L. Lambertsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neurology
Subjects:
modified rankin scale
Scandinavian Stroke Scale
biomarkers
functional outcome
transient ischemic attack
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00448/full

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https://www.frontiersin.org/article/10.3389/fneur.2020.00448/full

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