Loss of function of the Drosophila Ninein-related centrosomal protein Bsg25D causes mitotic defects and impairs embryonic development

The centrosome-associated proteins Ninein (Nin) and Ninein-like protein (Nlp) play significant roles in microtubule stability, nucleation and anchoring at the centrosome in mammalian cells. Here, we investigate Blastoderm specific gene 25D (Bsg25D), which encodes the only Drosophila protein that is...

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Bibliographic Details
Main Authors: Michelle Kowanda, Julie Bergalet, Michal Wieczorek, Gary Brouhard, Éric Lécuyer, Paul Lasko
Format: Article
Language:English
Published: The Company of Biologists 2016-08-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/5/8/1040