A Novel Multi-Scale Modeling Approach to Infer Whole Genome Divergence

We propose a novel and simple approach to elucidate genomic patterns of divergence using principal component analysis (PCA). We applied this methodology to the metric space generated by M. musculus genome-wide SNPs. Distance profiles were computed between M. musculus and its closely related species,...

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Bibliographic Details
Main Authors: Eli Reuveni, Alessandro Giuliani
Format: Article
Language:English
Published: SAGE Publishing 2012-01-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.4137/EBO.S10194