A Novel Multi-Scale Modeling Approach to Infer Whole Genome Divergence
We propose a novel and simple approach to elucidate genomic patterns of divergence using principal component analysis (PCA). We applied this methodology to the metric space generated by M. musculus genome-wide SNPs. Distance profiles were computed between M. musculus and its closely related species,...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-01-01
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Series: | Evolutionary Bioinformatics |
Online Access: | https://doi.org/10.4137/EBO.S10194 |