Activity-Based Probes to Utilize the Proteolytic Activity of Cathepsin G in Biological Samples

Activity-Based Probes to Utilize the Proteolytic Activity of Cathepsin G in Biological Samples

Neutrophils, migrating to the site of infection, are able to release serine proteases after being activated. These serine proteases comprise cathepsin G (CatG), neutrophil elastase protease 3 (PR3), and neutrophil serine protease 4 (NSP4). A disadvantage of the uncontrolled proteolytic activity of p...

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Bibliographic Details
Main Authors: Timo Burster, Fabian Gärtner, Uwe Knippschild, Anuar Zhanapiya
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Chemistry
Subjects:
activity-based probes
cathepsin G
flow cytometry
CyTOF/mass cytometry
immune cells
serine proteases
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.628295/full

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https://www.frontiersin.org/articles/10.3389/fchem.2021.628295/full

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