Computational Screening and Analysis of Lung Cancer Related Non-Synonymous Single Nucleotide Polymorphisms on the Human Kirsten Rat Sarcoma Gene

Computational Screening and Analysis of Lung Cancer Related Non-Synonymous Single Nucleotide Polymorphisms on the Human Kirsten Rat Sarcoma Gene

The human KRAS (Kirsten rat sarcoma) is an oncogene, involved in the regulation of cell growth and division. The mutations in the KRAS gene have the potential to cause normal cells to become cancerous in human lungs. In the present study, we focus on non-synonymous single nucleotide polymorphisms (n...

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Bibliographic Details
Main Authors: Qiankun Wang, Aamir Mehmood, Heng Wang, Qin Xu, Yi Xiong, Dong-Qing Wei
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
mutation
single nucleotide polymorphism
functional effect
molecular dynamics simulation
structural analysis
Online Access:https://www.mdpi.com/1420-3049/24/10/1951

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https://www.mdpi.com/1420-3049/24/10/1951

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