Significance of Single-Nucleotide Variants in Long Intergenic Non-protein Coding RNAs

Significance of Single-Nucleotide Variants in Long Intergenic Non-protein Coding RNAs

Single-nucleotide variants (SNVs) are the most common genetic variants and universally present in the human genome. Genome-wide association studies (GWASs) have identified a great number of disease or trait-associated variants, many of which are located in non-coding regions. Long intergenic non-pro...

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Bibliographic Details
Main Authors: Hecun Zou, Lan-Xiang Wu, Lihong Tan, Fei-Fei Shang, Hong-Hao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
single-nucleotide variant
long/large intergenic non-protein coding RNA
disease susceptibility
transcription
biological function
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00347/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00347/full

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