Evaluation of the potential of dietary proteins as precursors of dipeptidyl peptidase (DPP)-IV inhibitors by an in silico approach

Synthetic inhibitors against the enzyme dipeptidyl peptidase (DPP)-IV, a serine protease implicated in the inactivation of incretin hormones, are currently used for the management of type 2 diabetes. The aim of the present study was to evaluate the potential of dietary proteins from various food com...

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Bibliographic Details
Main Authors: Isabelle M.E. Lacroix, Eunice C.Y. Li-Chan
Format: Article
Language:English
Published: Elsevier 2012-04-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464612000096