Sustained Immunoparalysis in Endotoxin-Tolerized Monocytic Cells

Sepsis is associated with a strong inflammatory reaction triggering a complex and prolonged immune response. Septic patients have been shown to develop sustained immunosuppression due to a reduced responsiveness of leukocytes to pathogens. Changes in cellular metabolism of leukocytes have been linke...

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Bibliographic Details
Main Authors: Christina K. Weisheit, Alexandra Klüners, Lennart Wild, Alexandra Casalter, Stefanie Heilmann-Heimbach, Sugirthan Sivalingam, Jan L. Kleiner, Stefan F. Ehrentraut, Andreas Hoeft, Stilla Frede, Heidi Ehrentraut
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/8294342