Early Markers of Sickle Nephropathy in Children With Sickle Cell Anemia Are Associated With Red Cell Cation Transport Activity

Early Markers of Sickle Nephropathy in Children With Sickle Cell Anemia Are Associated With Red Cell Cation Transport Activity

Abstract. The early stages of sickle cell nephropathy (SCN) manifest in children with sickle cell anemia (SCA) as hyperfiltration and proteinuria. The physiological conditions of the renovascular system are among the most conducive to hemoglobin S polymerization in the body and will magnify small ch...

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Bibliographic Details
Main Authors: John Brewin, Sanjay Tewari, Anke Hannemann, Halima Al Balushi, Claire Sharpe, John S. Gibson, David C. Rees
Format: Article
Language:English
Published: Wolters Kluwer 2017-12-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000002

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http://journals.lww.com/10.1097/HS9.0000000000000002

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